Safe Weight Loss Guide

Weight loss medicine is great for many people who want to lose weight. They like trying to lose weight easily by weight loss drugs, but fear of medication side-effects. However, medicine therapy is one of the ways the treatment of obesity, appropriate use of weight loss drugs can be very effective weight loss program. Currently regulated by the FDA, the indication for the drug to lose weight, there are two, they are the role of different mechanisms to achieve the purpose of weight loss. Next on the two kinds of weight loss for this medicine in clinical applications give a brief account.

The first one is the scientific name Orlista (Roche defibrase trade names) of the drug, is a lipase inhibitor, its role in inhibiting gastrointestinal digestion of fat. When eating, the digestive system to secrete lipase eat fat (neutral fat) is broken down into smaller, can be absorbed by fat particles, which were in the intestinal digestion and absorption. Orlistat combined with lipase, inhibition of intestinal lipase in the decomposition of fats, oils and fats so eat because he can not be absorbed and eliminated from the body. According to the results of clinical trials, Orlistat can block about 30 percent of a meal of fat absorption, thereby reducing the absorption of calories and lose weight. Orlistat metabolism is mainly excreted through the gastrointestinal tract, only a very small fraction (<2%) by renal metabolism. As a result of medicine is a major role in blocking fat absorption, so medication may emerge during the oil will be, increased defecation and other gastrointestinal side effects. Proposed to take the drug during the need to tie in with the low-fat diet, to reduce the oil will be troubled. Long-term use of this drug is also recommended to add fat-soluble vitamins (such as vitamins A, D, E).

The second is the scientific name of the drug Sibutramine is a serotonin and serotonin-norepinephrine reuptake inhibitor. The role of this mechanism of drug in the central nervous system, using drugs after the body of serotonin and norepinephrine concentrations increased, resulting in reduced appetite and increase the effectiveness of the heat consumption, and weight loss. In addition to the effects of weight loss, in a period of 18 months of the STORM trial results showed that after weight loss, persistent use of drugs in comparison to the use of a placebo group also had better body weight to maintain the effect. During the medication side effects often have constipation, dry mouth, heart palpitations, but the majority of these side effects can be tolerated, if under the supervision of the physician is safe to use. If you are taking antidepressants are not suitable for patients with the medicine.

Members of the public claims to have weight loss products efficacy of another feast for the eyes, but really are not many effects, some drugs may even cause physical harm. Safe and effective weight loss drug to be tested numerous clinical trials to determine its efficacy, indications, side effects and cost-effectiveness is acceptable to the listing. At present, the use of approved long-term weight loss is only the two drugs, the future will have new listing of the drug. However, not all are suitable for people with weight loss drugs, such as children, pregnant or breast-feeding women, adverse reactions to drugs or who experience a major illness are not suitable for the use of drugs.

What drugs to use weight reduction, drug use and use of the timing of doses, have to be in the doctor’s assessment and directed to take the next judge, do not use their own purchase. The basis of weight loss must be based on a good diet, appropriate exercise and a healthy lifestyle, the supporting medical treatment and can make smooth the way towards successful weight loss, increased confidence.